Intramolecular reactions of N-nitrenes: oxidation of 3-amino-2-(2.4-dimethoxyphenylpropyl)quinazolin-4(3H)-one
Abstract
Oxidation of the title compound (3) and its gem-dimethyl-substituted analogue (10) in methanol gave the tetracyclic products (5) and (7). respectively. A solution of compound (5) in methanol was converted on standing into the cyclopentane ring-containing compound (8) whose structure was confirmed by X-ray crystallography.