SCHEDULED MAINTENANCE
Reaction of N-(de-cyclopropylmethyl)diprenorphine (3) with [1-11C]cyclopropanecarbonyl chloride (2), itself prepared from cyclotron-produced [11C]carbon dioxide, followed by reduction with LiAIH4, provides a fast and efficient route to carbon-11 labelled diprenorphine (7), a new radioligand for the study of the opiate receptor system in vivo.
S. K. Luthra, V. W. Pike and F. Brady, J. Chem. Soc., Chem. Commun., 1985, 1423 DOI: 10.1039/C39850001423
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