Enantioselective synthesis of (R)- or (S)-2-alkylglutaraldehydic acid methyl esters via chiral organotin enamines
Abstract
Nucleophilic addition of chiral organotin enamines to electrophilic alkenes is described; a minor modification of experimental conditions gave the other enantiomer of 2-alkylglutaraldehydic acid methyl esters.