Issue 4, 1985

2-Azabicyclo[2.2.0]hexane-3,5-dione, a new building block for carbapenem nuclei

Abstract

2-Azabicyclo[2.2.0]hexane-3,5-dione is synthesized via photopyridone formation from 4-(t-butyldimethylsilyloxy)- or 4-alkoxy-2-pyridone followed by mild acid hydrolysis and reacts with a variety of alcohols or thiols to give 4-alkoxycarbonyl- or 4-alkylthiocarbonyl-methylazetidin-2-ones.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1985, 189-190

2-Azabicyclo[2.2.0]hexane-3,5-dione, a new building block for carbapenem nuclei

N. Katagiri, M. Sato, S. Saikawa, T. Sakamoto, M. Muto and C. Kaneko, J. Chem. Soc., Chem. Commun., 1985, 189 DOI: 10.1039/C39850000189

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