Procedure for the simultaneous determination of tartaric and citric acids and total carbonate by potentiometric titrimetry and its application to antacid analysis

Abstract

The application of a linear algebraic method to the potentiometric titration of a mixture of tartaric and citric acids and sodium carbonate and sodium hydrogen carbonate (previously treated with strong acid), permits the determination of the concentration of each individual acid and the total equivalent of carbonate in antacids. It is also possible to determine individual concentrations of sodium carbonate and sodium hydrogen carbonate by combining the results of the described titration with the acidimetric titration of a sample previously treated with an excess of strong base.