5,6,7,8-Tetrahydroquinolines. Part 7. Synthesis of 8-cyano-5,6,7,8-tetrahydroquinolines; di-isopropylcyanamide, a new reagent for cyanation of organometallics
Abstract
Di-isopropylcyanamide (1) is an effective reagent for the conversion of 8-lithio-5,6,7,8-tetra-hydroquinolines into 8-cyano-5,6,7,8-tetrahydroquinolines. 8,8-Dicyano derivatives are not formed. A convenient synthesis of the reagent from disodium cyanamide is described.