Nucleic acid binding drugs. Part 11. The structure of 7-methylellipticine
Abstract
The molecular geometry of the title compound has been determined by X-ray diffraction. The crystal has unit-cell dimensions a= 4.042(2), b= 19.655(4), c= 16.343(2)Å, β= 94.48(2)°, space group P21/n and Z= 4. The final R= 0.048 for 806 unique reflections. The ability of various ellipticines to intercalate with DNA was also studied using molecular graphics.