Issue 0, 1984

Bredt's rule. Part 6. The synthesis of 5-phenyl-1-azabicyclo[3.3.1 ]nonan-2-one,a bridgehead amide

Abstract

6-Oxo-3-phenylpiperidine-3-propanoic acid, prepared from dimethyl 4-cyano-4-phenylheptanedioate, has been reduced selectively to the corresponding amine and then cyclised thermally or via its acid chloride to 5-phenyl-1-azabicyclo[3.3.1]nonan-2-one.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1984, 2669-2670

Bredt's rule. Part 6. The synthesis of 5-phenyl-1-azabicyclo[3.3.1 ]nonan-2-one,a bridgehead amide

G. L. Buchanan, J. Chem. Soc., Perkin Trans. 1, 1984, 2669 DOI: 10.1039/P19840002669

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