New metabolic products of Verticillium lecanii. Part 1. 3β-Hydroxy-4,4,14α-trimethyl-5α-pregna-7,9(11)-diene-20S-carboxylic acid and the isolation and characterisation of some minor metabolites
Abstract
The isolation is described of two insecticidal hydroxycarboxylic acids, C25H38O3 and C25H38O4, from entomopathogenic strains of the fungus Verticillium lecanii grown on Czapek Dox medium. Minor products from these fermentations include a number of related C25 compounds and 3-methyl-lumichrome. The C25H38O3 acid is shown by X-ray crystallography to be 3β-hydroxy-4,4,14α-trimethyl-5α-pregna-7,9(11 )-diene-20S-carboxylic acid.