Biosynthesis of betaenone B, phytotoxin of Phoma betae Fr.
Abstract
The incorporation of [1-13C]-, [2-13C]-, [1,2-13C]-acetate, and [Me-13C]methionine, indicated that betaenone B was biosynthesized from eight acetate units via a polyketide pathway, and all C-methyl groups expect the C-14 methyl were derived from methionine.