β-Hydroxydecanoylthioester dehydraes. Steric course at substrate C–4 in the enzyme–catalysed allylic rearrangement
Abstract
The pro-(4R)hydrogen is lost in the enzyme-catalysed rearrangement of the N-acetylcysteinamine thioseter of E-dec-2-enoic acid to the corresponding thioester of Z-dec-3-enoic acid.