Issue 0, 1983

Nucleophilic displacement of N-aryl and heteroaryl groups. Part 5. Conversion of 2-aminopyridines into 2-pyridones

Abstract

2-Ethoxycarbonyl-1-(2-pyridyl)pyridinium cations (3)(easily prepared from 2-aminopyridine and the appropriate pyrylium salt) are converted by dilute NaOH at 25 °C into 1-(substituted 2-pyridylcarbonyl)-2-pyridones (7). Compounds (7) are readily hydrolysed to 2-pyridones.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1983, 2623-2627

Nucleophilic displacement of N-aryl and heteroaryl groups. Part 5. Conversion of 2-aminopyridines into 2-pyridones

A. R. Katritzky and R. Awartani, J. Chem. Soc., Perkin Trans. 1, 1983, 2623 DOI: 10.1039/P19830002623

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