Acamelin, an allergy-inducing benzofuranoquinone extractive of Australian blackwood has been synthesized from 3-methoxypyrocatechol in six steps. The key step involved formation of a 2-methylbenzofuran by the intramolecular Witting reaction of an ortho-acetoxybenzyl bromide.
B. A. McKittrick and R. Stevenson, J. Chem. Soc., Perkin Trans. 1, 1983, 2423 DOI: 10.1039/P19830002423
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