Micellar methylating agents: (long-chain-alkyl)dimethylsulphonium iodides
Abstract
Dodecyl-, hexadecyl-, and octadecyl-dimethylsulphonium iodide were found to methylate efficiently various nucleosides, hydroxy aromatic compounds, and thiols at pH 8–11 and 50–70 °C. The optimum conditions and the mechanism of the reaction are discussed briefly in relation to the micellar reaction characteristics.