Conversion of tetrahydro-γ-carbolines into hexahydro[1,2]diazepino[5,4-b]indoles via ylide intermediates. X-Ray crystal structure determination of 9-bromo-2,3-dimethyl-1,2,3,4,5,6-hexahydro[1,2]diazepino[5,4-b]indole

Abstract

N-Amination of 2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles with N-alkyl-O-tosylhydroxylamines followed by base treatment gave 1,2,3,4,5,6-hexahydro-2,3-dialkyl[1,2]diazepino[5,4-b]indoles, the structure of one of which was determined by spectroscopic evidence and an X-ray structure analysis.