Triorganotin and triorganolead derivatives of N-acetylamino-acids

Abstract

Triorganotin and triorganolead derivatives of N-acetylglycine (AcGly), N-acetyl-α-alanine (AcAla), and N-acetylmethionine (AcMet), SnR₃(AcGlyO)(R = Me, Buⁿ, or Ph), PbR₃(AcGlyO)(R = Me or Ph), SnR₃(AcAlaO)(R = Me, Buⁿ, or Ph), PbPh₃(AcAlaO), SnR₃(AcMetO)(R = Me or Ph), and PbPh₃(AcMetO), have been prepared from MR₃(OH)(R = Me or Ph) or (SnBUⁿ₃)₂O and the appropriate N-acetylamino-acid. According to i.r., Raman, and Mössbauer data the compounds are five-co-ordinate and polymeric in the solid state. The MR₃ groups are co-ordinated by unidentate carboxylic groups and the oxygen of CO_amido. Co-ordination by NH groups is excluded. The compounds are essentially monomeric in solutions of CHCl₃, C₆H₆, acetone, tetrahydrofuran, or pyridine. In dimethyl sulphoxide co-ordination occurs to form five-co-ordinate species.