Asymmetric syntheses of the enantiomerically pure trifunctional (R)-3-hydroxy esters (7)–(10) can be achieved by baker's yeast reduction of the hydrolysed β-keto carboxylates (2)–(5) instead of by reduction of the corresponding ester.
M. Hirama, M. Shimizu and M. Iwashita, J. Chem. Soc., Chem. Commun., 1983, 599 DOI: 10.1039/C39830000599
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