Free radical substitution. Part 37. The effect of solvent on the atomic chlorination of 1-substituted butanes and related compounds

Abstract

Experimental results reported in this paper show that the relative selectivity of atomic chlorination of 1-substituted butanes and related compounds is greatly influenced by the phase and by solvents. Solvents can be divided into three classes: (a) inert, (b) solvents which decrease the selectivity, and (c) solvents which increase the selectivity. The second group solvate the transition state and the third group solvate the chlorine atoms.