An analysis of errors in estimating association constants and molar extinction coefficients from spectrophotometric data for 1 : 1 molecular complexes. Application to literature data

Abstract

Association constants K and molar extinction coefficients ε of 1 : 1 molecular complexes are caIculated from literature data and it is shown how the experimental error and the choice of the concentration of the reagents contributes to their respective standard deviations. Some indexes which are useful in pointing out aspects of the data ara also presented. An empirical attempt is made to analyse current criteria for estimating the reliability of the parameters, and to see to what extent they are well grounded.