Issue 0, 1982

Synthesis of 1,2,3,9b-tetrahydro-9b-hydroxy-1-phenylpyrrolo[2,1-a]isoindol-5-one via the hydrazinolysis of 2-phenyl-2(2-phthalimidoethyl)indan-1,3-dione

Abstract

Hydrazinolysis of 2-phenyl-2-(2-phthalimidoethyl)indan-1,3-dione gave 1,2,3,9b-tetrahydro-9b-hydroxy-1-phenylpyrrolo[2,1-a]isoindol-5-one via the conversion of 2-(2-aminoethyl)-2-phenylindan1,3-dione into the carbinolamine which underwent ring expansion followed by a transannular cyclisation.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1982, 2783-2786

Synthesis of 1,2,3,9b-tetrahydro-9b-hydroxy-1-phenylpyrrolo[2,1-a]isoindol-5-one via the hydrazinolysis of 2-phenyl-2(2-phthalimidoethyl)indan-1,3-dione

T. A. Crabb, A. Patel, R. F. Newton, B. J. Price and M. J. Tucker, J. Chem. Soc., Perkin Trans. 1, 1982, 2783 DOI: 10.1039/P19820002783

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