Issue 0, 1982

Anthracyclines. Part 1. The synthesis of racemic daunomycinone and some related tetrahydronaphthacenequinones

Abstract

New tetrahydronaphthacenequinones, which are related in structure to the aglycones of the antitumour drugs adriamycin and daunomycin, have been synthesised. Racemic daunomycinone has been prepared by a new, mild procedure utilising a phthalide intermediate for annelation.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1982, 2227-2238

Anthracyclines. Part 1. The synthesis of racemic daunomycinone and some related tetrahydronaphthacenequinones

M. J. Broadhurst and C. H. Hassall, J. Chem. Soc., Perkin Trans. 1, 1982, 2227 DOI: 10.1039/P19820002227

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