Propellane type derivatives of uric acid. X-Ray structure of 9-acetyl-4,5-(1-methoxyethylidenedioxy)-4,5-dihydrouric acid
Abstract
The chlorination of uric acid (1) in acetic anhydride yields an acetoxonium chloride (2), previously formulated as 5-acetoxy-9-acetyl-4-chloro-4,5-dihydrouric acid, which on methanolysis affords the corresponding cyclic orthoacetate (3); new structures were established by chemical, spectroscopic, and X-ray methods.