2-Cyclopropaneglyoxylic acid: a probe for the mechanism of hydrogen transfer by lactate dehydrogenase and by N-benzyl-1,4-dihydronicotinamide
Abstract
Reduction of cyclopropaneglyoxylic acid by lactate dehydrogenase and by model systems for both lactate and alcohol dehydrogenases occurs without cleavage of the three-membered ring implying that radical intermediates are improbable in these reactions.