Total synthesis of (±)-14α-methyl-19-norsteroids
Abstract
Trans-1,6-Dimethylbicyclo[4.3.0]nonane-2,7-dione was converted, in six steps, into a mixture of (±)-3-methoxy-14-methyl-14α-estra-1,3,5(10),9(11)-tetraen-17-one and the corresponding Δ8-isomer.