The cis-binding of inosine 5′-monophosphate and guanosine 5′-monophosphate to cobalt(III) in 1:1 metal-nucleotide complexes; X-ray crystal structures of ternary complexes with ethylenediamine
Abstract
X-Ray structural studies on the ternary complexes [Co(en)2(OH2)2][Co(5′-IMP)2(OH2)4]Cl2·4H2O (1) and [Co(en)2(OH)2)2][Co(5′-GMP)2(OH2)4]Cl2·4H2O (2)(en = ethylenediamine; 5′-IMP = inosine 5′-monophosphate; 5′-GMP = guanosine 5′-monophosphate) show that they are isomorphous and that cobalt binds to two symmetry-related nucleotide moieties in the cis-position through the N(7) atoms on the bases; this mode of binding is observed for the first time in a 1:1 metal–nucleotide complex.