Issue 1, 1982

Magnitude of the kinetic isotope effect for the oxidative demethylation of anisole and [Me-2H3]anisole: a new and simple criterion for assessing model systems for cytochrome P450 dependent mono-oxygenases

Abstract

The data from the oxidative demethylation of anisole, [Me-2H3] anisole by rat liver microsomes and ten model systems shed light on the mechanisms of O-demethylation and can be used to classify the model systems.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1982, 55-56

Magnitude of the kinetic isotope effect for the oxidative demethylation of anisole and [Me-2H3]anisole: a new and simple criterion for assessing model systems for cytochrome P450 dependent mono-oxygenases

J. R. L. Smith, R. E. Piggott and P. R. Sleath, J. Chem. Soc., Chem. Commun., 1982, 55 DOI: 10.1039/C39820000055

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