Issue 1275, 1982

Systematic errors in manual area measurement of skewed chromatographic peaks

Abstract

The systematic errors inherent in four methods of manual graphical chromatographic peak-area measurement are examined. Skewed peaks are simulated based on the exponentially modified gaussian equation. The errors in the peak-area measurements are calculated as a function of peak asymmetry. The Condal-Bosch trapezoidal method is seen to be largely unaffected by peak skew.

Article information

Article type
Paper

Analyst, 1982,107, 606-610

Systematic errors in manual area measurement of skewed chromatographic peaks

M. F. Delaney, Analyst, 1982, 107, 606 DOI: 10.1039/AN9820700606

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