Gas-chromatographic determination of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (methyl-CCNU). Part I. Cyclisation to a substituted aminooxazoline
Abstract
Methods for the gas-chromatographic determination of methyl-CCNU employing cyclisation to the substituted aminooxazoline have been explored. These procedures were found to be unsatisfactory for the determination of the drug in body fluids.