Jump to main content
Jump to site search

Issue 0, 1982
Previous Article Next Article

Acid- and base-catalysed reactions of 4β,5β- and 4α,5α-epoxyandrostane-3,17,19-trione

Abstract

The acid- and base-catalysed reactions of 4β, 5β- and 4α, 5α-epoxyandrostane-3,17,19-triones (2) and (7) have been examined to see if epoxide opening in these compounds would result in elimination of the C-10 substituent and the subsequent formation of estrone (25). However, the products obtained indicated that epoxide solvolysis or rearrangement concomitant with epoxide opening is the predominant mode of reaction under the conditions examined.

Back to tab navigation

Article type: Paper
DOI: 10.1039/P19820002611
J. Chem. Soc., Perkin Trans. 1, 1982, 2611-2615

  •   Request permissions

    Acid- and base-catalysed reactions of 4β,5β- and 4α,5α-epoxyandrostane-3,17,19-trione

    H. Mastalerz and P. Morand, J. Chem. Soc., Perkin Trans. 1, 1982, 2611
    DOI: 10.1039/P19820002611

Search articles by author

Spotlight

Advertisements