Preparation of tetrahydroindolizines from pyridinium and isoquinolinium ylides
Abstract
Carbonyl- and nitrile-stabilised pyridinium and cyclic azonium methylides condense with chalcones to form tetrahydroindolizines and analogous fused pyrrolidines. The stereochemistry is illuminated by 13C and 1H n.m.r. spectroscopy. Several incorrect literature structures are rectified.