Issue 21, 1981

Oxidative cleavage of peptide and protein disulphide bonds by gold(III): a mechanism for gold toxicity

Abstract

The oxidative cleavage of disulphide bonds to form the sulphonic acid derivatives is shown to be an important reaction of AuX4(X = Cl, Br) with proteins and peptides; the implications of this reaction for the toxicity of gold compounds are discussed.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1981, 1111-1114

Oxidative cleavage of peptide and protein disulphide bonds by gold(III): a mechanism for gold toxicity

P. L. Witkiewicz and C. F. Shaw, J. Chem. Soc., Chem. Commun., 1981, 1111 DOI: 10.1039/C39810001111

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements