Total synthesis of (±)-solavetivone; X-ray crystal structure of 2-hydroxy-6,10-dimethylspiro[4.5]dec-6-en-8-one
Abstract
(±)-Solavetivone (1) was synthesized by a new spiro-annelation reaction and a unique regio- and stereo-selective reduction of the spiro-dienone (4) to give (5), the structure of which has been determined by X-ray crystal-lography.