Asymmetric synthesis of a new proline analogue
Abstract
The 1,3-dipolar cycloaddition to ethylene of N-glycosylnitrones, formed in situ from the partially protected d-mannose- or d-ribose-oximes and various glyoxalates, gave compounds which could be transformed into both enantiomers of 3-t-butoxycarbonyl-isoxazolidine and derivatives thereof.