Epoxidation using triphenylphosphine–diethyl azodicarboxylate: synthesis of methyl 3,4-anhydro-α- and -β-D-tagatofuranosides
Abstract
Facile syntheses of the title compounds have been achieved by the one-step reaction of methyl α- or β-D-fructofuranoside with triphenylphosphine and diethyl azodicarboxylate in dimethylformamide; no blocking groups were necessary.