A short synthesis of (±)-phyllodulcin (1), a sweet principle of Hydrangea serrata Seringe var. thunbergii Sugimoto, from the enaminone (2) by annelation with dimethyl 3-oxaglutarate is described.
N. Takeuchi, K. Ochi, M. Murase and S. Tobinaga, J. Chem. Soc., Chem. Commun., 1980, 593 DOI: 10.1039/C39800000593
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