Deacylation of amides: removal of the acyl side-chain from cephamycin derivatives
Abstract
Diphenylmethyl (6R,7S)-7-amino-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-Δ3-cephem-4-carboxylate (9) is obtained from a cephamycin C derivative by treatment of an imino chloride intermediate with o-aminobenzenethiol.