C-alkylation of αβ-acetylenic esters using electrochemically generated intermediates
Abstract
Electrolysis at a platinum cathode of ethyl alk-2-ynoates in the presence of an excess of alkyl iodide in hexamethylphosphoramide or dimethylformamide solution containing tetra-n-butylammonium iodide gave the corresponding non-conjugated dialkylation products, ethyl 2,2-dialkylalk-3-ynoates, in good yield.