Tritium nuclear magnetic resonance spectroscopy. Part 10. Distribution of tritium in some labelled nitrogen heterocyclic compounds

Abstract

Pyridine, methylpyridines, quinoline, isoquinoline, phenanthridine, and nicotine have been labelled with tritium, using pre-reduced platinum dioxide and tritiated water. The regiospecificity and extent of labelling have been determined directly by ³H n.m.r. In instances of non-uniform labelling, the predominant effect seems to have a steric origin. The hydrogen chemical shifts for phenanthridine are reported for the first time.