Reactions of heterocycles with thiophosgene. Part 8. Reactions of NN′-bis-(2-isothiocyanatophenyl)-NN′-diformyl-1,2-diaminoethane
Abstract
Reactions of NN′-bis-(2-isothiocyanatophenyl)-NN′-diformyl-1,2-diaminoethane (4), prepared by fission of 1,2-bis(benzimidazol-1-yl)ethane (3) with thiophosgene and base, are described with a variety of nucleophiles. Aliphatic diamines give rise to 16–20-membered rings. Some reactions of the 16-ring compound (8) are also described.