Steroids and related studies. Part 48. A chandonium iodide analogue possessing an acetylcholine-like moiety
Abstract
A chandonium iodide analogue containing anacetylcholine-like moiety, 17a-(2-acetoxyethyl)-3β-pyrrolidino-17a-aza-D-homoandrost-5-ene dimethiodide (1), 17a-(2-hydroxyethyl)-3β-pyrrolidino-17a-aza-D-homoandrost-5-ene dimethiodide (22), and some monoquaternary derivatives have been prepared. Both (1) and (22) possess a marked neuromuscular blocking activity.