Nim-p-methoxyphenylsulphonylhistidine, a new derivative for peptide synthesis
Abstract
The p-methoxyphenylsulphonyl group attached at the Nim function of histidine can be quantitatively cleaved by trifluoroacetic acid in the presence of dimethyl sulphide at room temperature within 1 h; the Nim-tosyl group was also cleaved under similar conditions, but at a slower rate.