Reductive isomerisation in superacidic media: evidence for a 1,3 hydride shift in a steroid
Abstract
The major component of the reaction of 7β-methyl-14-iso-oestr-4-ene-3,17-dione in HF–SbF5–methyl-cyclopentane at 0 °C has shown to result from 1,3 hydride shift followed by kinetically controlled intermolecular hydride transfer.