5α,6α-Cholesterol oxide forms a strong physical complex with DNA which, on incubation, leads to a significant amount of covalent attachment of steroid to DNA; both this oxide and its 3-acetate give adducts with neutral thiols and heterocyclic amines, the former alone responding to acidic catalysis.
G. M. Blackburn, A. Rashid and M. H. Thompson, J. Chem. Soc., Chem. Commun., 1979, 420 DOI: 10.1039/C39790000420
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