Regiocontrolled head-to-tail coupling of alkylthioallyl carbanions with allylic halides via lithium alkylthioallyl borates
Abstract
Reaction of lithium alkylthioallyl borates (3), prepared from alkylthioallyl-lithium (1) and trialkylboranes at –78 °C, with allylic halides (2) gives head-to-tail 1,5-dienes (4) in good yields.