Acid-catalysed backbone rearrangement involving the C–D ring junction in normal steroid series
Abstract
Protic and Lewis acids cause partial backbone rearrangement involving the C–D ring junction in the normal steroid series with ring contraction and formation of 12,14α-cyclo-12,13-seco-5α-cholest-13(17)-ene compounds. 12-Methylene rather than 13-methyl rearrangement is suggested and a revision of a previously proposed structure is given.