Issue 12, 1978

Cleavage of the aminoadipoly side chain of cephamycin C to the (6R, 7S)-7-amino-7-methoxy derivative

Abstract

(6R,7S)-Benzhydryl 7-amino-7-methoxy-3-carbamoyloxymethylceph-3-em-4-carboxylate (6a), which is an important intermediate for the synthesis of various analogues with a wide spectrum of antibiotic activity, has been obtained from cephamycin C (1a)via the oxamic acid intermediate (3a).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1978, 517-518

Cleavage of the aminoadipoly side chain of cephamycin C to the (6R, 7S)-7-amino-7-methoxy derivative

M. Shiozaki, N. Ishida, K. Iino and T. Hiraoka, J. Chem. Soc., Chem. Commun., 1978, 517 DOI: 10.1039/C39780000517

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