Issue 4, 1978

Mechanism of formation of 4-methyl- and 4-chloro-2-nitrophenol in the nitration of 4-methyl- and 4-chloro-anisole, respectively, in aqueous sulphuric acid

Abstract

The title reactions involve capture by water of the ipso-Wheland intermediates, followed by loss of methanol, then of nitronium ion to give solvent-caged ion pairs of para-substituted phenol and nitronium ion which can combine before or after diffusion apart.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1978, 180-181

Mechanism of formation of 4-methyl- and 4-chloro-2-nitrophenol in the nitration of 4-methyl- and 4-chloro-anisole, respectively, in aqueous sulphuric acid

R. B. Moodie, K. Schofield and G. D. Tobin, J. Chem. Soc., Chem. Commun., 1978, 180 DOI: 10.1039/C39780000180

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