Determination of theophylline in plasma: comparison of high-performance liquid chromatography and an enzyme multiplied immunoassay technique

Abstract

Plasma theophylline concentrations have been determined by both high-performance liquid chromatography and the enzyme multiplied immunoassay technique (EMIT). Comparison of the results showed a good correlation between the techniques. The faster processing time and smaller sample size makes EMIT the preferred technique when routine batch assays for theophylline are required.