Reactions of S-alkyl NN-disubstituted thioamide salts. Part 2. Orthothioamide derivatives
Abstract
NN-Disubstituted thioamide salts (1) with aqueous potassium cyanide readily give quaternary cyanides (3) which sometimes react further, yielding cyano-amides (4)via aminomalononitriles, e.g.(6). 2-Methylthio-2-morpholino-2-phenylacetonitrile (3a) on heating with morpholine or primary amines undergoes disproportionation, probably by a free radical mechanism.