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Issue 9, 1977
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Enolate anions as protecting groups for ketones during reduction by hydride

Abstract

The selective formation of enolate anions provides protection for carbonyl groups against reduction by lithium aluminium hydride. Any carbonyl group not so protected is reduced in a synthetically useful manner.

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Article information


J. Chem. Soc., Perkin Trans. 1, 1977, 1075-1079
Article type
Paper

Enolate anions as protecting groups for ketones during reduction by hydride

D. H. R. Barton, R. H. Hesse, C. Wilshire and M. M. Pechet, J. Chem. Soc., Perkin Trans. 1, 1977, 1075
DOI: 10.1039/P19770001075

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